CJC-1295 + Ipamorelin vs Tesamorelin Buyer Guide: GH-Support, VAT Evidence, COA Checks, and Price Per Mg

Short Answer

Pick CJC-1295 plus ipamorelin when you want the broader growth-hormone support stack: one GHRH signal plus one ghrelin-receptor signal. Pick tesamorelin when the comparison is specifically about visceral adipose tissue evidence.

They are close enough that buyers compare them, but they are not the same buy. CJC-1295 is the GHRH analog. Ipamorelin is the five-amino-acid growth-hormone secretagogue commonly stacked with it. Tesamorelin is a 44-amino-acid GHRH analog sold as Egrifta, EGRIFTA SV, and EGRIFTA WR in the regulated market, while PeptidePub also tracks research-style tesamorelin offers for price comparison.

Start with goal, then math, then proof. Use /peptides/cjc-1295 and /peptides/ipamorelin for stack basics, /peptides/tesamorelin for the VAT lane, /prices for price per mg, /vendors for vendor proof, and /methodology for the testing standard. PeptidePub already has /blog/cjc-1295-ipamorelin-buyer-guide for the stack by itself. This guide fills the buyer gap against tesamorelin.

What Buyers Are Actually Comparing

CJC-1295 with DAC binds albumin through its Drug Affinity Complex and stays active for days. CJC-1295 without DAC clears much faster and is more accurately Mod GRF 1-29, so the label needs to say which version it is.

Ipamorelin is Aib-His-D-2-Nal-D-Phe-Lys-NH2, also called NNC 26-0161. It binds GHS-R1a, the ghrelin receptor, and prompts pituitary growth-hormone release. The reason buyers pair it with CJC-1295 is simple: the two peptides hit different receptors.

Tesamorelin is also a GHRH analog, but the buyer reason is different. It has the cleaner visceral-fat evidence lane, especially around HIV-associated lipodystrophy research.

Think of the comparison this way: CJC-1295 plus ipamorelin equals a two-peptide GH-support stack, sometimes sold as a FIT Stack blend. CJC-1295 supplies the GHRH signal. Ipamorelin supplies the ghrelin-receptor signal. Tesamorelin supplies a GHRH analog with stronger VAT-specific human trial data.

That framing keeps the purchase practical. Do not compare only the names. Compare mechanism, evidence fit, price per mg, and whether the vendor proves the exact vial.

Evidence and Benefit Fit

Do not pretend the evidence is equal. The best buy depends on the benefit lane.

CJC-1295 has a strong hormone-response rationale. In Teichman 2006, a single DAC-version injection raised mean plasma GH 2-fold to 10-fold for 6 or more days and mean IGF-1 1.5-fold to 3-fold for 9 to 11 days. The estimated half-life was 5.8 to 8.1 days, and multiple doses kept mean IGF-1 above baseline for up to 28 days.

Ipamorelin adds selectivity to the stack story. Raun 1998 described it as the first selective growth-hormone secretagogue, with GH release and no ACTH or cortisol levels significantly different from GHRH stimulation. That is why it became a common partner for CJC-1295 rather than just another GH peptide name.

The clinical limitation is worth knowing. In a 114-patient postoperative ileus trial, time to first tolerated meal was 25.3 hours with ipamorelin vs 32.6 hours with placebo, but p=0.15, so the endpoint missed statistical significance.

Tesamorelin is the VAT evidence pick. PeptidePub guide data lists about 15% to 18% CT-measured visceral adipose tissue reduction at 26 weeks in pooled Phase 3 HIV-lipodystrophy trials, sustained to 52 weeks in continuers.

In JAMA 2014, tesamorelin changed visceral adipose tissue by -34 cm2 over 6 months vs +8 cm2 with placebo. The treatment effect was -42 cm2, p=0.005. Liver fat also improved, with a net treatment effect of -2.9 percentage points, p=0.003. Subcutaneous adipose tissue did not move the same way: treatment effect -6 cm2, p=0.37.

That is the clean buyer takeaway. CJC-1295 plus ipamorelin is the broader GH-support stack with a hormone-pulse rationale. Tesamorelin is the stronger VAT-specific human-evidence buy.

Price Comparison

Ascension Peptides is the clearest real-vendor anchor in the PeptidePub catalog: USA shipping, Kovera Labs listed, 77 COA records, COA verified true, and PEPTIDEPUB confirmed at 50% off.

Ascension CJC-1295 10 mg is $73 list, $7.30 per mg list, $36.50 after code, and $3.65 per mg effective.

Ascension ipamorelin 5 mg is $44 list, $8.80 per mg list, $22 after code, and $4.40 per mg effective.

Ascension tesamorelin 5 mg is $50 list, $10.00 per mg list, $25 after code, and $5.00 per mg effective.

Ascension FIT Stack, listed as CJC-1295 plus ipamorelin 10 mg, is $57 list and $28.50 after code. If treated only as total stated mg, that is $5.70 per total mg list and $2.85 per total mg effective. That can look like the cheapest route, but component split and component-level COA proof matter.

Separate Ascension CJC-1295 10 mg plus ipamorelin 5 mg totals $117 list and $58.50 effective after code. That is 15 mg total, not the same as a 10 mg blend unless the blend component split is known. Adding Ascension tesamorelin 5 mg brings that price context to $167 list and $83.50 effective, but that is context, not a suggested stack.

The wider catalog spread matters. CJC-1295 includes Peptide Society 10 mg at $49.99, AMP 5 mg and EZ 5 mg at $38, Atomik 5 mg at $45, Aero 10 mg at $69.99, Ascension 10 mg at $73, Main 2 mg at $39.99, Main 5 mg at $49.99, Main 10 mg at $74.99, and World Wide 5 mg at $191.

Ipamorelin includes AMP 10 mg and EZ 10 mg at $44, Ascension 5 mg at $44, Double R 10 mg at $49.99, Glacier 10 mg at $51.99, Atomik 10 mg at $56, Level Up 10 mg at $58, Mile High 10 mg at $59.99, Main 5 mg at $44.99, Main 10 mg at $69.99, MD Innovative 10 mg at $70, and World Wide 5 mg at $107 or 10 mg at $174.

Tesamorelin has a big spread too: Ascension 5 mg $50, Atomik 10 mg $55 and 20 mg $110, Aero 10 mg $64.99, AMP 10 mg $68, EZ 10 mg $68, Glacier 10 mg $67.99 and 20 mg $117.99, Improved 5 mg $89 and 10 mg $130, Level Up 10 mg $75, Mile High 10 mg $79.99, Valkyrie 10 mg $100, MD Innovative 10 mg $120 and 20 mg $200, and World Wide 5 mg $228 or 10 mg $464.

Useful price-per-mg checkpoints: Peptide Society CJC-1295 10 mg is about $5.00 per mg, AMP and EZ CJC-1295 5 mg are $7.60 per mg, Aero CJC-1295 10 mg is about $7.00 per mg, and World Wide CJC-1295 5 mg is $38.20 per mg. AMP and EZ ipamorelin 10 mg are $4.40 per mg, Double R 10 mg is about $5.00 per mg, and World Wide 10 mg is $17.40 per mg. Atomik tesamorelin 10 mg is $5.50 per mg, Aero 10 mg is about $6.50 per mg, AMP and EZ 10 mg are $6.80 per mg, Glacier 20 mg is about $5.90 per mg, and World Wide 10 mg is $46.40 per mg.

Use /tools/cost-per-dose when the choice comes down to price per draw or value after PEPTIDEPUB. For this category, effective price matters more than sticker price.

Blend and Label Checks Before Checkout

For CJC-1295, the label must say whether it is with DAC or without DAC. Plain CJC-1295 often means the DAC version. No-DAC is more accurately Mod GRF 1-29 and clears in under an hour.

For a CJC-1295 plus ipamorelin blend or FIT Stack, the COA should support both components, not just total purity or a generic blend name. For tesamorelin, verify the vial says tesamorelin, not sermorelin, CJC-1295, or a vague GHRH blend. The buyer is paying for a specific peptide.

A strong COA shows batch or lot match, named third-party lab, report date, identity by mass spec, purity by HPLC or UPLC, net content or fill amount, heavy metals when available, and endotoxin and sterility when relevant. PeptidePub Testing Score checks 7 items: net content, purity, identification, heavy metals, sterility, endotoxins, and contaminant screening.

Vendor and Deal Workflow

Use the same buying reflex every time: compare the compound at /prices, check the vendor at /vendors, read /methodology for the proof standard, then apply the deal after the vial passes.

Ascension is the clearest current discount example because PEPTIDEPUB is confirmed at 50% off and /go/bodybuilding-health is a verified affiliate route. Still, do not rank purely by lowest sticker price. A cheaper GH-peptide vial loses value if the COA does not verify identity, amount, and batch match.

Total mg can mislead on blends. FIT Stack may look cheaper by total stated mg than separate vials, but separate vials give cleaner component control and easier component-level verification.

Which One Should You Check First

Choose CJC-1295 plus ipamorelin when you want the popular GH-support stack lane, care about the two-receptor rationale, and want to compare separate vials against a convenience blend.

Choose tesamorelin when you are specifically comparing visceral-fat evidence and want the peptide with the strongest VAT-specific human trial data in this lane.

Choose separate CJC-1295 and ipamorelin vials when label clarity and component-level COA proof matter more than blend convenience. Choose FIT Stack only after checking whether the vendor provides component-level evidence for both CJC-1295 and ipamorelin, and after calculating the effective price using the discount code.

Compare /prices/cjc-1295, /prices/ipamorelin, and /prices/tesamorelin side by side before buying.

FAQ

Is CJC-1295 plus ipamorelin the same as tesamorelin? No. CJC-1295 and tesamorelin are both GHRH analogs, but CJC-1295 plus ipamorelin is a two-pathway stack because ipamorelin works through the ghrelin receptor.

Which has stronger visceral-fat evidence? Tesamorelin. PeptidePub guide data lists about 15% to 18% CT-measured VAT reduction at 26 weeks, and JAMA 2014 found -34 cm2 vs +8 cm2 over 6 months.

Is FIT Stack cheaper than separate vials? In the Ascension catalog, FIT Stack is $57 list and $28.50 after code for 10 mg total stated blend. Separate Ascension CJC-1295 10 mg plus ipamorelin 5 mg totals $117 list and $58.50 effective, but that is not the same mg mix.

What should a blend COA show? Both named components, batch or lot, identity, purity, and ideally net content. A generic total-purity report is weaker.

Bottom Line

CJC-1295 plus ipamorelin is the broader GH-support stack buy. Tesamorelin is the VAT-evidence buy. Match the peptide to the goal, verify identity and COA proof, compare price per mg and cost per dose, then use the strongest real deal code. Do not buy CJC-1295, ipamorelin, FIT Stack, or tesamorelin without checking /prices and /vendors first.