Novi vs Medvi: Lowest GLP-1 Price vs Coaching Support in 2026

Novi is the better fit if you want the lower tracked all-in compounded GLP-1 price, simple month-to-month access, free 2-day shipping, and coaching included. Start with Novi if price is the deciding factor.

Medvi is the better fit if you want a more guided program with clinician review, 1:1 guidance, metabolic reporting, coaching, tablets, and a brand Wegovy route. Start with Medvi if support and format options matter more.

Both providers require clinician review. Neither guarantees a prescription. The pages reviewed include compounded GLP-1 access, and Medvi also advertises brand Wegovy pill or injection access through a $99 membership plus medication cost.

Quick price read: PeptidePub's Novi review lists compounded semaglutide from $174/month and compounded tirzepatide from $283/month. Novi's official homepage says semaglutide starts at $199 for the first month with no contract. Medvi's official GLP-1 page says semaglutide starts at $179 for the first month with no contract, then refills are locked at $299. PeptidePub's Medvi review lists GLP-1 injections from $179/month, tablets from $249/month, and brand Wegovy pill or injection at $99 membership plus medication cost.

Pricing and what is included

Novi's advantage is lower tracked ongoing pricing. Its official homepage says the semaglutide program starts at $199 for the first month and includes, if eligible, a GLP-1 prescription, a 4-week supply each month, needed supplies, clinician check-ins, dose-adjustment questions, side-effect support, and coaching. It also says pricing is all-in, with no hidden fees, no separate membership, no minimum commitment, and no long-term contract.

The local Novi review is the better price comparison for ongoing buyer research: compounded semaglutide from $174/month and compounded tirzepatide from $283/month. It also notes consultation included, free 2-day shipping, unlimited clinician support, coaching included, and cancel-anytime positioning. One practical caveat: Novi says shipped or dispensed prescriptions cannot be returned or refunded.

Medvi's official page starts lower for month 1, then becomes clearer on refills. It says semaglutide starts at $179 for the first month with no contract, and refills are locked at $299. That offer includes physician review, a personalized plan, 1:1 guidance, a metabolic report, and prescription medication shipped to the door.

Medvi also advertises free expedited delivery, doctor-led plans and coaching, no hidden fees, HSA/FSA approved language, 24/7 support, and over 500,000+ patients. Its local review adds tablets from $249/month and a brand Wegovy pill or injection route at $99 membership plus medication cost. So Medvi's $179 is best treated as a first-month entry price, with $299 as the key official refill number.

Care model and support

Novi is streamlined. The buyer takes a 3-minute quiz, gets a licensed clinician review, may complete a quick tele-visit, and receives medication at the provided address if prescribed. After that, the program includes a 4-week supply, clinician access, dose guidance, side-effect support, and coaching.

That is enough support for many self-directed buyers. PeptidePub rates Novi 4.3/5 and frames it as best for budget-conscious patients who want low all-in pricing, free 2-day shipping, coaching, unlimited clinician support, and no long-term contracts.

Medvi is more structured. Its flow centers on online evaluation, clinician review, a personalized care plan, medication shipped to the door if appropriate, regular provider check-ins, nutrition guidance, dose optimization, side-effect management, and health coaching.

PeptidePub rates Medvi 4.1/5 and frames it as best for people who want full support, video consultations, regular provider check-ins, nutritional guidance, and proactive dose management. Medvi's official page also says OpenLoop Health is a network of US-licensed doctors with exclusionary criteria, and that an OpenLoop clinician determines eligibility after checkout.

The tradeoff is simple: Novi gives enough clinical support for many price-sensitive, self-directed buyers. Medvi may be worth more if accountability, coaching, tablets, metabolic reporting, regular check-ins, or brand-route access are part of the decision.

Medication formats and evidence expectations

Novi's reviewed pages emphasize compounded semaglutide and compounded tirzepatide injections. Medvi's reviewed pages include GLP-1 injections, dissolvable tablets, and a brand Wegovy pill or injection route through a $99 membership plus medication cost.

That difference matters. Do not assume compounded tablets have the same evidence base as FDA-approved injectable semaglutide or tirzepatide. The best obesity trial data cited here is for injections.

In the STEP 1 trial, semaglutide 2.4 mg injection produced mean body weight change at week 68 of -14.9% versus -2.4% with placebo. At least 5% weight loss occurred in 86.4% of semaglutide users versus 31.5% of placebo users.

In SURMOUNT-1, tirzepatide injection produced average weight reductions at 72 weeks of 16.0% for 5 mg, 21.4% for 10 mg, and 22.5% for 15 mg, versus 2.4% with placebo. At least 5% weight loss occurred in 89% to 96% of tirzepatide users versus 28% with placebo.

For drug-specific context, use the semaglutide and tirzepatide guides. For the broader tradeoff, use compounded versus brand GLP-1.

Safety, legality, and buyer checks

The safety caveat applies to both providers. FDA says unapproved GLP-1 versions, including semaglutide and tirzepatide, do not undergo FDA review for safety, effectiveness, or quality before marketing. FDA also says compounded drugs are not FDA-approved, and compounded drugs should be used only when a patient's medical needs cannot be met by an FDA-approved drug.

FDA adverse-event reports as of July 31, 2025 included 605 associated with compounded semaglutide and 545 associated with compounded tirzepatide, with likely underreporting. FDA concerns include warm shipments or inadequate ice packs, fraudulent compounded drugs, dosing errors, doses beyond approved labels, salt forms such as semaglutide sodium and semaglutide acetate, illegal online sales, and products falsely labeled research purposes or not for human consumption.

Shortage policy also changed. FDA says the tirzepatide injection shortage was resolved December 19, 2024, and the semaglutide injection shortage was resolved February 21, 2025. FDA also says enforcement-discretion periods tied to those shortages have ended for 503A and 503B compounders.

Before paying either provider, verify the licensed clinician, exact medication and format, pharmacy name and state license, compounded versus brand status, concentration, dosing instructions, shipping temperature handling, refill price, cancellation deadline, refund rules, and side-effect support.

For Novi, ask whether $174 or $199 is the active first-month or ongoing semaglutide price, what tirzepatide renewal costs, which pharmacy dispenses, and whether any minimum commitment appears at checkout. For Medvi, ask whether $179 renews at $299, what tirzepatide costs, whether tablets are $249 on the selected plan, which brand medications are available, and what medication cost applies on top of the $99 membership.

Who should choose Novi versus Medvi

Choose Novi if you want the lower tracked all-in compounded semaglutide or tirzepatide pricing, simple injection access, free 2-day shipping, coaching included, and month-to-month cancellation. It is the cleaner fit if you are self-directed and mostly want a lower-cost prescription pathway with clinician access for questions, dose guidance, and side-effect support.

Novi may not fit if you want tablets, brand-name access, or a longer public track record. Its reviewed offer is mainly about compounded injections.

Choose Medvi if you want a more guided program with video consultations, regular provider check-ins, nutrition guidance, health coaching, metabolic report language, and 24/7 support. It is also the better fit if you want tablets or want to explore a brand Wegovy route with a membership plus medication cost.

Medvi may not fit if price is the main filter. Its official FAQ says $179 for the first month and $299 locked refills, while Novi's local review shows $174/month semaglutide and $283/month tirzepatide.

For more provider comparisons, read Novi vs SkinnyRx, Eden Health vs Medvi, and is Medvi legit. For broader shopping context, use cheapest semaglutide online and best online weight-loss program.

FAQ

Which is cheaper, Novi or Medvi? Novi has the lower tracked ongoing prices in PeptidePub's local review: $174/month for semaglutide and $283/month for tirzepatide. Medvi's official page says $179 first month and $299 locked refills.

Does Medvi offer more support than Novi? Yes. Medvi emphasizes physician review, a personalized plan, 1:1 guidance, a metabolic report, doctor-led plans, coaching, and 24/7 support. Novi includes clinician support, dose guidance, side-effect support, and coaching, but its main advantage is price and simplicity.

Does either provider offer tirzepatide? PeptidePub's local review says Novi offers tirzepatide from $283/month and Medvi offers compounded semaglutide and tirzepatide. Verify final checkout pricing and medication format.

Does either provider offer tablets or brand-name medication? Novi's reviewed page emphasizes compounded injections. Medvi lists tablets from $249/month and brand Wegovy pill or injection at $99 membership plus medication cost.

Are compounded GLP-1s FDA approved? No. FDA says compounded drugs are not FDA-approved and are not reviewed for safety, effectiveness, or quality before marketing.

Bottom line

Novi is the lower-price, simpler GLP-1 access pick. Medvi is the more guided support and format-flexibility pick. Start with Novi for the lower all-in GLP-1 entry price. Start with Medvi for coaching-heavy support, tablets, or a brand-route membership option.