SS-31 + MOTS-c Buyer Guide: Separate Vials, COA Proof, and Real Price Per Mg

Short Answer: Separate Vials Usually Win on Proof and Price Math

SS-31 and MOTS-c fit complementary mitochondrial research lanes, but putting them in one vial does not automatically create a better buy. Separate vials make it easier to verify identity, purity, net content, lot number, concentration, and price per mg for each peptide. They also let you replace one component without rebuying the other.

A blend earns consideration only when its label states the exact milligrams of SS-31 and MOTS-c separately and a lot-matched third-party report verifies both identities and both quantities. Otherwise, the apparent convenience hides the two numbers needed to judge value.

Start with the live SS-31 table at /prices/ss-31 and the MOTS-c table at /prices/mots-c. Then check the sellers at /vendors and enter the planned amounts in /tools/cost-per-dose. Compare the final checkout total, not just the vial price.

Two Peptides, Two Mitochondrial Research Lanes

SS-31, also called elamipretide or MTP-131, is a mitochondria-targeting tetrapeptide. It reversibly binds cardiolipin in the inner mitochondrial membrane, supporting cristae structure, electron-transport-chain flux, and ATP production.

MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded within the mitochondrial 12S rRNA region. Research connects it with AMPK signaling, metabolic homeostasis, glucose handling, and exercise-responsive signaling.

The simple buyer map is SS-31 for the inner-membrane and cardiolipin lane, and MOTS-c for the metabolic-signal and AMPK lane. That mechanistic complement is a reason to compare them together, not proof that a blend outperforms either peptide alone. For deeper MOTS-c coverage, see the MOTS-c peptide guide and MOTS-c Buyer Guide.

What the Human and Preclinical Data Show

The clearest human SS-31 signal comes from Roshanravan et al. In this randomized, double-blind, placebo-controlled trial, researchers enrolled 39 healthy adults ages 60 to 85 with poorly functioning muscle mitochondria. Participants were 46% female.

A single two-hour elamipretide infusion at 0.25 mg/kg per hour increased mitochondrial ATP-production capacity immediately after treatment. The percent-change comparison reached P = 0.045, while the absolute change was P = 0.055. There was no difference on day 7, no significant change in resting mitochondrial coupling, and no significant improvement in fatigue resistance. The practical takeaway is a human ATP-capacity signal, not a guaranteed performance result.

MOTS-c has a different evidence base. Reynolds et al. studied 10 healthy young men and found that exercise increased skeletal-muscle MOTS-c 11.9-fold. Circulating MOTS-c increased 1.6-fold during exercise and 1.5-fold after exercise, then moved toward baseline after four hours of rest.

In mice, Lee et al. reported that MOTS-c activated AMPK through effects on the folate cycle and purine biosynthesis, while improving insulin sensitivity and metabolic homeostasis.

No cited study directly compares an SS-31 plus MOTS-c blend with separate vials. That leaves buyers with a straightforward standard: compare the products on component-level proof, flexibility, and final cost.

Current SS-31 Prices and Best Verified Value

The PeptidePub catalog snapshot checked July 29, 2026 includes these SS-31 offers:

• Ascension: 10 mg for $60
• Atomik: 50 mg for $199
• Valkyrie: 50 mg for $185
• World Wide: 10 mg for $193 or 50 mg for $656
• Double R: 50 mg for $139.99
• Main: 7 mg for $44.99 or 10 mg for $54.99
• Mile High: 10 mg for $69.99
• Aero: 10 mg for $64.99
• Viper: 10 mg for $39.99
• Valor: 10 mg for $49.99

Double R 50 mg is the strongest verified SS-31 checkpoint. The $139.99 list price falls to about $118.99 with the 15% PEPTIDEPUB code, or about $2.38 per mg. Its vendor profile shows Kovera Labs, COA verification, and 7 of 7 PeptidePub testing fields.

Ascension 10 mg falls from $60 to $30 with the confirmed 50% PEPTIDEPUB code. That is $3.00 per mg, backed by Kovera Labs, COA verification, and 6 of 7 fields.

Other effective prices are Valkyrie 50 mg at $166.50 after 10% off, or $3.33 per mg; Atomik 50 mg at about $169.15 after 15% PEPTIDEPUB15, or $3.38 per mg; Viper 10 mg at about $33.99 after 15% off, or $3.40 per mg; and Valor 10 mg at about $44.99 after 10% off, or $4.50 per mg.

Use /prices/ss-31 immediately before buying because prices, stock, and codes can change.

Current MOTS-c Prices and Two-Peptide Cart Math

Peptide Society 40 mg is $69.99 list and about $55.99 after the 20% PEPTIDEPUB code. That is about $1.40 per mg. Its vendor profile has verified IS-Lab proof and 4 of 7 testing fields, but confirm the report for the current MOTS-c lot itself.

Atomik 40 mg is $99 list and about $84.15 after 15% PEPTIDEPUB15, or about $2.10 per mg. Its profile shows Kovera Labs, COA verification, and 6 of 7 fields.

Ascension 10 mg is $49 list and $24.50 after the confirmed 50% PEPTIDEPUB code, or $2.45 per mg. The matching Kovera report KVR-2026-B16BA6 measured 11.09 mg against a 10 mg product size, with 99.588% purity, LC-MS identity, endotoxin pass, sterility showing no growth, and heavy metals under limits.

A same-vendor Double R cart puts SS-31 50 mg at about $118.99 after code and MOTS-c 10 mg at about $33.99 after code, for roughly $152.98 before shipping. Keep the unit costs separate because the vial sizes differ.

The lowest-unit-cost cross-vendor example combines Double R SS-31 at about $2.38 per mg with Peptide Society MOTS-c at about $1.40 per mg. The tradeoff is two sellers, potentially two shipping charges, and different testing depth.

Compare the final total, shipping, usable vial size, and exact lot proof. Then use /tools/cost-per-dose to translate the planned amounts into usable value.

Separate Vials vs Blends: The COA Decision

Separate vials give each peptide its own identity, purity, net-content result, lot number, concentration, and price-per-mg calculation. They also preserve ratio flexibility and let you replace one component without buying the other again.

A blend can simplify inventory and reconstitution when its fixed component ratio already matches the plan. The downside is that the same fixed ratio removes flexibility, combined purity is harder to interpret, and a report verifying only one ingredient proves nothing about the other.

For any SS-31 plus MOTS-c blend, require:

• The exact labeled mg of SS-31 and MOTS-c separately
• Identity confirmation for both peptides
• Quantitative content for both components
• A lot number matching the vial
• A named third-party lab and verifiable report ID
• Sterility, endotoxin, heavy-metal, and contaminant results where available

Do not divide a blend price by total labeled mg and treat both components as equally priced. Allocate value only after each component amount is known and verified. A label claiming 50 mg total is not enough if it never shows how much is SS-31 and how much is MOTS-c.

For the complete proof workflow, use How to Read a Peptide COA Before You Buy. The examples in the Peptide COA Underfilled Batch Guide show why high purity does not establish the milligrams inside a vial.

When separate vials win, reconstitute and calculate each concentration independently. The reconstitution calculator handles BAC-water volume, concentration, and U-100 syringe-unit math without forcing both peptides into one ratio.

Vendor Proof and Deal Workflow

Use the same sequence for every cart:

1. Verify the exact peptide and lot.
2. Compare each vial on /prices/ss-31 and /prices/mots-c.
3. Apply the confirmed code and calculate effective price per mg.
4. Add shipping.
5. Compare the separate-vial total with any blend.
6. Confirm the current vendor evidence at /vendors.

Current catalog testing-depth checkpoints are Double R and World Wide at 7 of 7 fields; Ascension, Atomik, Glacier, and Mile High at 6 of 7; Valor at 5 of 7; Peptide Society at 4 of 7; and Viper, Main, and Valkyrie at 3 of 7.

Those scores describe vendor-published testing coverage. They do not prove that every current SS-31 or MOTS-c lot has the same file, so match the report to the product before checkout. /methodology explains how PeptidePub evaluates the seven testing fields. Best Research Peptide Vendors for Third-Party Testing provides a wider vendor comparison.

The codes used in these price examples are:

• PEPTIDEPUB: 50% at Ascension
• PEPTIDEPUB: 20% at Peptide Society
• PEPTIDEPUB: 15% at Double R and Viper
• PEPTIDEPUB: 10% at Valkyrie, Valor, Main, and Mile High
• PEPTIDEPUB15: 15% at Atomik

Codes and stock can change, so verify the live listing. Once the proof and price checks pass, /go/bodybuilding-health is the verified affiliate route when that seller fits the cart.

FAQ

Are SS-31 and MOTS-c the same type of mitochondrial peptide?

No. SS-31 targets cardiolipin and inner-membrane function. MOTS-c is a mitochondrial-derived signaling peptide associated with AMPK and metabolic homeostasis.

Is an SS-31 plus MOTS-c blend better than separate vials?

Not automatically. A blend can simplify inventory when its fixed ratio fits the plan. Separate vials usually offer cleaner component proof, flexible ratios, easier concentration math, and clearer price comparisons.

What is a strong SS-31 price per mg right now?

The strongest verified checkpoint in the July 29 catalog is Double R 50 mg at about $2.38 per mg after the 15% PEPTIDEPUB code. Ascension follows at $3.00 per mg after its confirmed 50% code.

What is a strong MOTS-c price per mg right now?

Current checkpoints range from about $1.40 per mg at Peptide Society after code to $2.10 at Atomik and $2.45 at Ascension. Those offers differ in vial size and published testing depth, so price per mg is only one part of the decision.

What must a blend COA show?

It should verify both identities, the quantity of each component, an exact lot match, a named lab, and a verifiable report. Broader sterility, endotoxin, heavy-metal, and contaminant fields add useful depth. A purity number or total-mg claim alone is not enough.

Bottom Line

Default to separate SS-31 and MOTS-c vials when they provide stronger lot-specific proof, better component control, and a lower final cost. Choose a blend only when the label and lot-matched third-party report verify both peptides and both quantities, the fixed ratio fits the plan, and the checkout value beats separate vials.

For the current July 29 snapshot, Double R sets the verified SS-31 value checkpoint at about $2.38 per mg after code. MOTS-c checkpoints run from about $1.40 per mg at Peptide Society to $2.10 at Atomik and $2.45 at Ascension after their respective codes. The lowest sticker math is not necessarily the best cart if shipping doubles or the exact lot lacks component-level proof.

Before buying:

• Compare live SS-31 offers at /prices/ss-31.
• Compare live MOTS-c offers at /prices/mots-c.
• Check the exact vendor and lot evidence at /vendors.
• Apply the current verified discount code.
• Add shipping and calculate the final price per mg for each peptide.
• Reject any blend that hides either component quantity.

The buying reflex is simple: check PeptidePub before purchasing. The right choice is the cart that combines clear lot proof, the component flexibility you want, and the strongest final value.