EnhanceMD Review: Flat-Rate GLP-1 Pricing With Lab Monitoring

What Is EnhanceMD?

EnhanceMD is a telehealth platform offering compounded semaglutide and tirzepatidewith a key differentiator: flat-rate pricing. Most providers increase your cost as your dose goes up. EnhanceMD charges the same price whether you're on a starting dose or a maintenance dose — no surprise price hikes.

They also include metabolic lab testing every 6 months, which most competitors charge extra for or skip entirely. This gives your provider real data to guide dosing decisions, not just how the scale is moving.

How Much Does EnhanceMD Cost?

Here's the current pricing breakdown:

• GLP-1 Core (semaglutide): $49 first month, then $212/month
• GLP-1 Advanced (tirzepatide): $99 first month, then $280/month
• GLP-1 Elite (semaglutide + tirzepatide combo): $189 first month, then $322/month
• Microdosing tirzepatide: $169/month
• NAD+ injections: $169/month
• Lab testing: Included every 6 months

The key advantage is flat-rate pricing. Many providers start low but charge $300-$500/month once you hit higher doses. With EnhanceMD, $212/month is $212/month regardless of your semaglutide dose. The low first-month pricing ($49 for semaglutide, $99 for tirzepatide) also makes it easy to try the platform with minimal risk. They also offer a money-back guarantee if you're found ineligible. For price context, see our guide on finding the cheapest semaglutide online.

What's Included

• ✓ Medical consultation with a licensed provider
• ✓ Compounded semaglutide, tirzepatide, or combo prescription
• ✓ Flat-rate pricing — same cost at every dose
• ✓ Metabolic lab testing every 6 months
• ✓ Money-back guarantee if found ineligible
• ✓ Dose adjustments as needed
• ✓ Ongoing provider support

Pros

• Flat-rate pricing with no dose escalation — pay the same whether you're on 0.25mg or 2.4mg semaglutide
• Low first-month pricing — $49 for semaglutide and $99 for tirzepatide to get started
• Lab monitoring included — metabolic testing every 6 months at no extra cost
• Unique combo option — GLP-1 Elite combines semaglutide and tirzepatide
• Microdosing option — tirzepatide microdosing at $169/mo for a gentler approach
• Money-back guarantee — refund if you're not medically eligible
• NAD+ available — additional treatments beyond weight loss

Cons

• Ongoing price is mid-range — $212/mo for semaglutide is competitive but not the cheapest available
• Compounded only — no brand-name Ozempic/Wegovy pathway
• Injections only — no oral, lozenge, or drop formats
• Less established — smaller platform compared to some competitors
• No dedicated coaching — provider support but not a structured coaching program

Who Is EnhanceMD Best For?

EnhanceMD is a great fit if you:

• Want pricing predictability — know exactly what you'll pay at every dose
• Value lab monitoring to track metabolic health beyond just weight
• Are interested in trying GLP-1s at a low entry cost ($49 first month)
• Want the option of a semaglutide + tirzepatide combo
• Prefer a data-driven approach to weight loss with regular lab work

It may not be the best fit if you want the absolute lowest monthly price (consider Eden Health at $149/mo), need multiple medication formats beyond injections (see ShedRx), or want brand-name medications.

EnhanceMD vs Other Providers

See our full provider comparison page for a more detailed breakdown of all options.

How to Get Started

1. Complete the online health questionnaire at enhance.md
2. Choose your plan: Core, Advanced, Elite, or Microdosing
3. A licensed provider reviews your profile and prescribes if appropriate
4. Your medication ships to your door
5. Complete metabolic lab testing at the 6-month mark for data-driven adjustments