Updated May 2026

Compare GLP-1 Weight Loss Programs

Side-by-side comparison of online programs for semaglutide, tirzepatide, and other GLP-1 medications. See what each one costs, what's included, and which fits your situation.

At a glance

Pricing can change — always confirm directly with the program before enrolling.

Most Options

SkinnyRx

From $179/mo

Semaglutide, tirzepatide, oral options

Best selection — injectable, oral, and sublingual options for both semaglutide and tirzepatide

See Options
Most Support

Direct Meds

From $249/mo

Semaglutide + tirzepatide (injectable + sublingual drops)

All-inclusive pricing with dedicated nurse support from day one

Take the Quiz
Best Value

Eden Health

From $149/mo

Semaglutide, tirzepatide, brand-name options

Flat-rate pricing that doesn't increase as your dose goes up

Start Intake

Medvi

From $179/mo

Semaglutide + tirzepatide (injectable + oral tablets)

Lowest intro price ($179 first month) with dietitian support and money-back guarantee

Check Eligibility

Gala GLP-1

From $149/mo

Compounded tirzepatide, microdose tirzepatide, brand-name Ozempic, HRT

Women seeking GLP-1 weight loss and hormone therapy (HRT) from one provider

See Options

Breeze Meds

From $199/mo

Compounded semaglutide (injectable + oral), compounded tirzepatide (oral), sermorelin

No-commitment pay-as-you-go model without subscription lock-in

Get Started

Novi

From $174/mo

Compounded semaglutide, compounded tirzepatide

One of the lowest all-in monthly prices on compounded semaglutide

Check Eligibility

Shed

From $199/mo

Semaglutide, tirzepatide (injectable, sublingual, oral), brand-name Wegovy/Zepbound

Most medication format options (oral, sublingual, injectable) plus a weight loss guarantee

Take the Quiz

EnhanceMD

From $49 first mo

Semaglutide, tirzepatide, sema+tirz combo, microdose tirzepatide, NAD+

Flat-rate dosing with no escalation costs, plus integrated lab monitoring

Get Started

Peter MD

From $99/mo

Semaglutide, tirzepatide, TRT, ED meds, hair loss, NAD+

Men who want weight loss, TRT, ED, and hair loss treatment from one provider

See Options

TMates

From $199/mo

Semaglutide (oral + injectable), tirzepatide (oral + injectable), TRT, NAD+

Broadest geographic coverage including Puerto Rico with 24/7 access

Take the Quiz

Compounded semaglutide, compounded tirzepatide, NAD+, sermorelin

Fitness-focused patients who want GLP-1 weight management alongside longevity treatments (NAD+, sermorelin)

Start Assessment

Brand-name price check

NovoCare direct self-pay pricing is now part of the comparison

NovoCare Pharmacy lists eligible Wegovy pill patients from $149/month for 1.5 mg and 4 mg doses. It also lists Wegovy pens at $199/month for two starter fills through June 30, 2026, then $349/month for standard pen doses and $399/month for Wegovy HD 7.2 mg.

That is a meaningful brand-name alternative to compounded telehealth programs, but it is not one universal price. Eligibility, prescription status, form, dose, offer windows, and NovoCare Pharmacy terms all matter.

Check NovoCare pricing →

Price alerts

Get notified when any of these programs run a sale

We track pricing across every program on this page. When a provider drops prices or offers an exclusive discount, our subscribers hear first.

Program details

What each program includes and who it's best for.

SkinnyRx

Most Options

Semaglutide, tirzepatide, oral options

From $179/mo

Best selection — injectable, oral, and sublingual options for both semaglutide and tirzepatide

What's included

  • Injectable, sublingual + tablet formats
  • Free overnight shipping
  • Provider check-ins
  • No contracts

Direct Meds

Most Support

Semaglutide + tirzepatide (injectable + sublingual drops)

From $249/mo

All-inclusive pricing with dedicated nurse support from day one

What's included

  • Dedicated nursing team
  • Free 1–2 day shipping
  • HSA/FSA accepted
  • No contracts, cancel anytime
  • LegitScript certified

Eden Health

Best Value

Semaglutide, tirzepatide, brand-name options

From $149/mo

Flat-rate pricing that doesn't increase as your dose goes up

What's included

  • Same price at every dose
  • Free expedited shipping
  • 24/7 care team messaging
  • No contracts or cancellation fees
  • All 50 states

Semaglutide + tirzepatide (injectable + oral tablets)

From $179/mo

Lowest intro price ($179 first month) with dietitian support and money-back guarantee

What's included

  • Free dietitian visits
  • 24/7 provider messaging
  • Lab testing included when needed
  • Money-back guarantee
  • 49 states

Compounded tirzepatide, microdose tirzepatide, brand-name Ozempic, HRT

From $149/mo

Women seeking GLP-1 weight loss and hormone therapy (HRT) from one provider

What's included

  • Microdosing from $149/mo
  • 24/7 support
  • Dose adjustments included
  • Medication switching at no cost
  • All 50 states

Compounded semaglutide (injectable + oral), compounded tirzepatide (oral), sermorelin

From $199/mo

No-commitment pay-as-you-go model without subscription lock-in

What's included

  • No subscription required
  • Pay as you go
  • Free discreet delivery
  • FSA/HSA eligible

Compounded semaglutide, compounded tirzepatide

From $174/mo

One of the lowest all-in monthly prices on compounded semaglutide

What's included

  • All-inclusive pricing
  • Free 2-day shipping
  • Unlimited clinician support
  • Coaching included
  • No long-term contracts

Semaglutide, tirzepatide (injectable, sublingual, oral), brand-name Wegovy/Zepbound

From $199/mo

Most medication format options (oral, sublingual, injectable) plus a weight loss guarantee

What's included

  • 10% body weight loss guarantee
  • Free shipping + coaching
  • Pivot tracking app
  • Unlimited provider appointments
  • FSA eligible

Semaglutide, tirzepatide, sema+tirz combo, microdose tirzepatide, NAD+

From $49 first mo

Flat-rate dosing with no escalation costs, plus integrated lab monitoring

What's included

  • Same price at every dose
  • Metabolic lab testing every 6 months
  • Telehealth consultations
  • Home delivery
  • Money-back guarantee if ineligible

Semaglutide, tirzepatide, TRT, ED meds, hair loss, NAD+

From $99/mo

Men who want weight loss, TRT, ED, and hair loss treatment from one provider

What's included

  • Price match guarantee
  • Free consultations
  • Free shipping
  • Baseline labs included (TRT)
  • All-inclusive pricing

Semaglutide (oral + injectable), tirzepatide (oral + injectable), TRT, NAD+

From $199/mo

Broadest geographic coverage including Puerto Rico with 24/7 access

What's included

  • All 50 states + Puerto Rico
  • 24/7 medical staff access
  • No contracts or initiation fees
  • SMS coaching
  • Discreet 2-3 day shipping

Compounded semaglutide, compounded tirzepatide, NAD+, sermorelin

From $159/mo

Fitness-focused patients who want GLP-1 weight management alongside longevity treatments (NAD+, sermorelin)

What's included

  • 3-month bundle savings ($159/mo sema, $179/mo tirz)
  • Provider-guided treatment plans
  • FDA-registered pharmacies
  • Discreet home delivery
  • HIPAA-compliant platform

How to pick the right one

1. Know what medication you're getting

Brand-name Wegovy and Zepbound are different from compounded semaglutide or tirzepatide. Make sure the program is clear about what you're actually receiving.

2. Check the total cost, not just the headline

Some programs include everything in one monthly price. Others charge separately for consultations, shipping, labs, or dose changes. Ask before you sign up.

3. Confirm they serve your state

Telehealth prescribing rules and pharmacy fulfillment vary by state. Don't waste time on intake if they can't ship to you.

4. Make sure you get real support

These medications can cause side effects and may need dose adjustments. Look for programs where you can actually talk to someone — not just get a prescription and be on your own.

Other wellness programs

These focus on wellness beyond weight loss. We list them separately so this page stays focused on helping you find the right weight loss option.

  • Sprout Health: NAD+ and wellness funnels. Learn more
  • Quad by Medvi: Quad therapy from Medvi. Learn more

Frequently asked questions

How did you choose these programs?

We list programs that are available through our affiliate network and that focus on GLP-1 weight loss medications. We're adding verified pricing, state coverage, and clinical details as we review each one. Affiliate compensation does not determine our editorial view.

Should I just pick the cheapest option?

Not necessarily. Price matters, but so does what's included — some programs bundle medication, shipping, and follow-up care into one price, while others charge separately. Check the total cost, not just the headline number.

What's the difference between compounded and brand-name GLP-1s?

Brand-name drugs like Wegovy and Zepbound are FDA-approved products from major manufacturers. Compounded versions are made by pharmacies and can be significantly cheaper, but they're not identical to the FDA-approved products. Both should be prescribed and monitored by a licensed clinician.

Can I use insurance or HSA/FSA?

Most compounded GLP-1 programs are cash-pay, but some accept HSA/FSA funds. Brand-name medications may be covered by insurance depending on your plan. Check with each program directly.

Ready to compare? Our top pick starts at $149/mo with flat-rate dosing.

Visit Eden Health →

GLP-1 prices change weekly. Stay ahead of it.

We monitor pricing across all the programs above and negotiate exclusive discounts. Get price drop alerts and deals before they expire.