TMates Review: 24/7 Access in All 50 States + Puerto Rico

What Is TMates?

TMates (tmates.com) is a telehealth platform offering weight loss medications, TRT, NAD+, hair loss, and skincare treatments. They claim over 40,000 patients and operate across all 50 states plus Puerto Rico — a broader footprint than many competitors. Their standout features include 24/7 medical staff access, SMS coaching, competitively priced compounded injectable semaglutide and tirzepatide, and brand Wegovy/Zepbound at $99/mo.

What They Offer

• Compounded semaglutide (injectable): from $158/month
• Compounded tirzepatide (injectable): from $167/month
• Brand Wegovy / Zepbound: $99/month (injectable, brand-name)
• Phentermine: $149/month (oral appetite suppressant)
• TRT: Testosterone replacement therapy
• NAD+: Longevity and cellular health treatments
• Hair loss: Prescription hair restoration options
• Skincare: Medical-grade skincare treatments

Pricing

Here's the current pricing breakdown (verified June 2026):

• Compounded semaglutide (injectable): from $158/month
• Compounded tirzepatide (injectable): from $167/month
• Brand Wegovy / Zepbound (injectable): $99/month
• Shipping: Discreet 2-3 day delivery
• Contracts: None — cancel anytime

At $158/month for compounded semaglutide and $167/month for compounded tirzepatide, TMates is now one of the more competitively priced compounded providers — and its $99/month brand Wegovy and Zepbound pricing is notable for anyone who wants the FDA-approved branded product. For a broader look at semaglutide pricing across providers, see our cheapest semaglutide online comparison and our compounded vs. brand GLP-1 guide.

Pros

• ✓ All 50 states + Puerto Rico — broader coverage than most competitors
• ✓ 24/7 medical staff — access to support any time, not just business hours
• ✓ SMS coaching — text-based support for accountability
• ✓ Brand or compounded — choose $99/mo brand Wegovy/Zepbound or lower-cost compounded injectables
• ✓ No contracts — cancel anytime without penalties
• ✓ Discreet 2-3 day shipping — fast and private delivery

Cons

• Trustpilot discrepancy — TMates' website claims a 4.9-star rating from 4,700+ Trustpilot reviews, but their actual Trustpilot profile may show different numbers. Always verify review claims independently.
• BBB billing complaints — some patients have reported billing issues through the Better Business Bureau
• GLP-1 pricing is injectable-only — compounded semaglutide and tirzepatide are offered as injectables; there's no compounded oral GLP-1 option (oral is limited to phentermine)

Who Is TMates Best For?

TMates is worth considering if you:

• Live in an underserved state or Puerto Rico where other providers don't operate
• Want 24/7 medical staff access, not just business-hours support
• Want competitively priced compounded injectables, or brand Wegovy/Zepbound at $99/mo
• Value no-contract flexibility with SMS coaching

It's probably not the best fit if you specifically want a compounded oral GLP-1, or if verified third-party reviews are a dealbreaker for you given the Trustpilot discrepancy below. Compare all options on our provider comparison page.