Provider ReviewUpdated May 2026

TMates Review: 24/7 Access in All 50 States + Puerto Rico

TMates offers semaglutide and tirzepatide in both oral and injectable forms across all 50 states and Puerto Rico, with 24/7 medical staff. But some review discrepancies deserve a closer look.

8 min read

Quick Verdict

Price

From $199/mo (semaglutide)

Best For

Patients in underserved states wanting 24/7 access

Our Rating

3.5 / 5

What Is TMates?

TMates (tmates.com) is a telehealth platform offering weight loss medications, TRT, NAD+, hair loss, and skincare treatments. They claim over 40,000 patients and operate across all 50 states plus Puerto Rico — a broader footprint than many competitors. Their standout features include 24/7 medical staff access, SMS coaching, and both oral and injectable formulations of semaglutide and tirzepatide.

What They Offer

  • Semaglutide (oral + injectable): $199-$225/month
  • Tirzepatide (oral + injectable): From $297/month
  • Phentermine: Available as an appetite suppressant option
  • TRT: Testosterone replacement therapy
  • NAD+: Longevity and cellular health treatments
  • Hair loss: Prescription hair restoration options
  • Skincare: Medical-grade skincare treatments

Pricing

Here's the current pricing breakdown:

  • Semaglutide (injectable): $199-$225/month
  • Semaglutide (oral): $199-$225/month
  • Tirzepatide (oral + injectable): From $297/month
  • Shipping: Discreet 2-3 day delivery
  • Contracts: None — cancel anytime

Pricing is competitive but not the cheapest. For a broader look at semaglutide pricing across providers, see our cheapest semaglutide online comparison and our compounded vs. brand GLP-1 guide.

Pros

  • All 50 states + Puerto Rico — broader coverage than most competitors
  • 24/7 medical staff — access to support any time, not just business hours
  • SMS coaching — text-based support for accountability
  • Oral + injectable options — flexibility for patients who prefer pills over needles
  • No contracts — cancel anytime without penalties
  • Discreet 2-3 day shipping — fast and private delivery

Cons

  • Trustpilot discrepancy — TMates' website claims a 4.9-star rating from 4,700+ Trustpilot reviews, but their actual Trustpilot profile may show different numbers. Always verify review claims independently.
  • BBB billing complaints — some patients have reported billing issues through the Better Business Bureau
  • Higher tirzepatide pricing — $297/month for tirzepatide is above average compared to competitors
  • Compounded only — no brand-name Ozempic/Wegovy or Mounjaro option

Caution: Review Discrepancy

TMates' website claims a 4.9-star Trustpilot rating from 4,700+ reviews. We recommend verifying this directly on Trustpilot before making a decision, as we've observed discrepancies between their claimed and actual review profiles. Additionally, the BBB lists billing-related complaints. Do your due diligence.

Who Is TMates Best For?

TMates is worth considering if you:

  • Live in an underserved state or Puerto Rico where other providers don't operate
  • Want 24/7 medical staff access, not just business-hours support
  • Prefer oral GLP-1 options over injectables
  • Value no-contract flexibility with SMS coaching

It's probably not the best fit if you want the lowest price (see Eden Health) or if verified third-party reviews are a dealbreaker for you. Compare all options on our provider comparison page.

Bottom Line

TMates offers genuine convenience with 24/7 access, broad state coverage including Puerto Rico, and both oral and injectable GLP-1 options. However, the Trustpilot review discrepancy and BBB billing complaints warrant caution. Verify their reviews independently and start with a single month before committing.

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